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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca567e584c32cc06d16f6fcd4073e374662333cb48962ce962c3ef2bad17fb1' 
  AND token = 'DkgiIQxV/ZRFixFpZdcnFZxT7/xDEb8apm+ILBISRE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}