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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e416d70f7c99a321c2917d0bee5cd3656fbf443b8e2ec7d20112c8cf4796dc18' 
  AND token = 'wCP/wZWQWdFKaQI4cICCBi9wCuCircokWsLYTzR4x6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}