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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f66d327ccc26897a1e92f5e15a2952eb860f5762500697889f6636e2b9c953' 
  AND token = 'O+bRCz2O9bcO8KUSUfsidj1Aqzy8ZilIryvVyHbwZww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}