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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165fa1232eb911e33c944b2ae329a0912a372c5a8330405b306ffb725401f78d' 
  AND token = 'tatUPLJu1ATewl42ICrpGhIqX+lqgNu3MiIPa2Y4L+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}