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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd9c3b2d2afdbb3edaf4d7c4bf08dff9492741a34693e32192959bcc9446137' 
  AND token = '9RYEo9RI4pV3z8GYfGzK4digHa9wmmYvGonAlYlecZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}