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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b74d6d2f62d6fa7147b55e41651c1a19253e6d95ffc688d8f54e39d71ac792e4' 
  AND token = 'lqPGQ0YDGRkroLjdj7cOUg4MMTcVR0aPFVAjLsCjiFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}