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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6df31b5e8346d37a1418116f304914e84b0d0c82351cbc1dd45af2b88b60a48a' 
  AND token = 'BszYF+A8kSeIM+XE403kXs8gOReBUsp9ey+tQi0uRCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}