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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea7ab4a6837b5965a429f3bf2e899966b0f0f769c61add1deca151e396324b6' 
  AND token = 'R1/v02fh7q0Ro0HMCcdTerTS/H0T3MeHyGTi7qZKWtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}