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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b817644caba06763b9f056978f700ed2ae29be3a8b2e62441ecfbef2e727707c' 
  AND token = '325ul+U4HAe0Hu4XpXie6/h90CTRM8RvQpLnasq0e+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}