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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0639b62247bc9cfe2ded5269fb7a77c46ab97337960f0e818e13cd278c0ea51' 
  AND token = 'vIrSF2n1bnT0hjs4JH30GsjHFfvTyYWUcGL06NYFvrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}