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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0b4616719a7b5bae12c4531f7d3f4ca1f44f5cbbaeb1258374a85a133b92257' 
  AND token = '6rwp9Pg/zvGgMzGKD5N0vPLUl8EgzFXRAoEb9OaB4C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}