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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8f2e0491884a2dad95e754b34919b97bdf0dd1205d278a377964ef3ee2c789e' 
  AND token = '0pLPybS8ma0MxEXvdQj8fcOUVXmkJnYzGW4yLG/S8z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}