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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '148983ef8f5e47829783c059da5d30f97eb1015e4339a9cb19b827266eee1477' 
  AND token = 'JN6xzgBLuebmDkxWICCFzKfH6nlC95tSibR3LBpSSiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}