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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8646e1c417d5803c059234aa66c8b2b3ba35953551d4de98457d1820d89efc29' 
  AND token = '9zR3PvzhgivdWMTE825yp7wvazERckCVCkmssktc6oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}