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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1bb2bd1f9b48776cb3d748ece8c300f750a794fb18ad75fcf66717aa65921e1' 
  AND token = 'K0JkQ+DhZE1ml23Y/eYeDZA5e4COXrvwu1PJIfRlQEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}