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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10c7353efb0d105b7424586120c30f7664be4b59d7e3f776dafb0a7b4a75838' 
  AND token = 'cBJSTWaEXj0P+0Ewoby93dsP3IIqd6Nj0MsWipwxcCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}