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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36a8d37ab304e0a0222fd343da2e7944761cf9aa6b56ca6acadc3287e4692ecf' 
  AND token = 'yIVPQ/nI0dRJeLB01tjC7sKC514NnAOh+hS0AfdZ2Fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}