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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b23b74b91953cc3de928b98ebeac9333b1b25cdba02f1279f7fb45f62b3cbc' 
  AND token = 'TjJ6L7ZgwJB+HzfKCv5Beo3466w5jmyIZWcmKrJkMfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}