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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4d2c359091c9e638a54b0501e17f1cbd17035fd6f969dd72c623aaeacfa532' 
  AND token = 'miRfGlrZW+Gzo+5lZu2Eeg8fbc5/QBisWCz0UOsHeBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}