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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bbacfdac4bf6bd851d1ec1441b11c7da040b7da960239bffa2ed845b79aa775' 
  AND token = 'LYFISTDxtiok5BGX9SRsSDckCkVtWLuvb0d/G26uT4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}