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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab884480d1c76e36b8e8225d86d9de161d6e7ac95545a2179ab4e6487fd55afd' 
  AND token = 'PK1DG1lq0LtsMm1xKvBMDXZWiKA+hekK+zMN3sMFGTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}