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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d3b4e5c6c8da7d40cd418deac23b0909416fa76338a5bc254b412a15300a3c' 
  AND token = 'Qm2/wwE8nvSLbYFEcDdxV2EIUfTBbtBkFp/S4gz09oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}