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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2674591a75c8f4488ca20aa7e5a5eab2d14a9e4f64bd6e288dfa09220e0ea77f' 
  AND token = 'qU2G+0BYuuTKiFAOaDWdy0i8TexP5eQCfRs2PwMKoFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}