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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ce078f0ce26a23be464e23cad4038d7bb0bdae5f8b338e24b9acae85ffb52c' 
  AND token = '4v7rn/MttW+zBLFlMyR//WDXWaQ6XS4H1ISc7gkaENc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}