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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44811e5c2682b9bfbe13deb72284e3ecda4437c72126df919388f0d70a5e3d6e' 
  AND token = 'El+7ivvhMQtiaC3Bv6kCsQhg3h056xPF8C5BE7Ys2iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}