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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74446bf4cf8535a1e2ed987630f194e4917aa2570b004777859df5c8f0a0d475' 
  AND token = 'X13l49gM3xDtpM5k94o4BCOkBvYrWmKnZ2+ldOVSuHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}