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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e3ebf1f0e70fa1b486e20bdf1eb0e5ea0ae3f0ae2e1114f23871a17db00a49' 
  AND token = 'DPsKTJJZFQE8HDKp7VVS6DUq9k7YrUIc7v+Gmz3V5sE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}