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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05f0118470de2da180049e3a1f7c965d1dd0de146ea972d91350c05e185cdd5' 
  AND token = 'R6xOayiXtj7l86dIrE793pubOvSpjEyQhH68RyDAIAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}