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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5adf05b97687c539c4129dea5480e5562203d75e04e91ceb874b431744861c' 
  AND token = 'wLRaa1k3AMwc5GfC7shAWDoDMAVPRGENCnsa7071kNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}