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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b66ad0acbb325af32df1e276b1b56c7d43ca92fcf074dea5014edf8f52b7857' 
  AND token = 'dtDiODn+jR+9OvaqGTsvoC+vvZxCK7RWf9r/NTsC8oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}