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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0594c14e0639554d476a37f43069d0ee69cb84149e1438c03593f38dde64e9' 
  AND token = 'BWtbR6+ciN2bPfTezQM/46HF8rw0KKsBesV6vkHM6xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}