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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fd8cf65ce79243f826e9a5ec8408b1e86e8931d653deafe63ceeb0ecc21274e' 
  AND token = 'xOIA1mw2+CnewP9uWmll+h592Ah83QK8UgP+Hql6lzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}