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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c8963ec03c6d3d76025cd84dbee51a67fb86abd95337ee5bfa8be719cc7383' 
  AND token = 'nhhweBHJIzJTBYcuK8NXl9jql59IruX8aqOa+UUSWbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}