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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e10197759c0eec9140e6555a2a25d71f5127175cbbb7b0eff98ac8872276b7d' 
  AND token = 'LqEJJ/Ac72waSLmoq5nrjzsCF2Ktex5aZtg3Y/+8Qsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}