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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b682b46a0a112f26ab3dee7feed2ba1ac36895ec1d2c815491eaa4ce7a617c6' 
  AND token = '+eP9NeDuMRQ0afJhwP0Ff+a9s0tWVaEWeMlXWxli7fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}