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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3888325dab72829539a7fe9982d7df7bc67d265df9f7d29fb6bf4c5c321bedbb' 
  AND token = 'N1YVuMfsTSLOvEC10v34Alq46UATzfawD/pe4UXPSRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}