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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1fc1cb3a21f06b70a8d85fe35106344612ce9c6537bc838051732588c04a5b0' 
  AND token = '++GQIy0DIENGTnFbKuCE2vtXkU3emPWFY3CcXJ87jDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}