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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51002f421e5de63bc3f7fb1bcdc4da5b101bed863b6a698d599cded61075c8d9' 
  AND token = 'FqG3fP3l02ZEhKRXJ4NWQO49nhQeaAW5s0ry9Mtg3ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}