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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5408c9356534b91f8e9d832d60604eb0e2a78c6c87603e3a7f744b6feb08fae4' 
  AND token = 'rOA/relbEkQhAT5Mn4PhshMxewQPkgFtK6Z6d4iTgPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}