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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c4134200e6da013dd086be851a0e468ab2e368a20fc9eb5ce708ddf879f6a5' 
  AND token = 'II55u5IAGBih0JxDwPamEEGBTs5WQl0h4WwOMkfQzD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}