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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '554d1521cbb32de1b5511941b4dfa54b794a1a00e521152c1cada3be25683a87' 
  AND token = 'xD1nEL9YkPDxlXUafBfAALKIuMoWrpXfT7P7LnfC+4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}