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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b716251a000a20dac27efb3b2d2d47fe4d65a78d7b52004309e3ac4b2ad1cc' 
  AND token = '75R2qxCY8kuyH2gdre46Rv6FMN345TLZyVIDwTMuBd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}