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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d21247dd9cdcf947bd014227f39f2bcf0231fb879a29342ed917f7b911d94c7' 
  AND token = 'c3G4XrL0xgHgQ02m5qFzVpJcQoCH/K3EhZ+OBd19bQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}