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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b57d0363e10b1c627393e1915390ad5e0a3d7b5096c4a337af11315f92e7e0f4' 
  AND token = 'qudJI/nMzk9QnWWg7mdhA+E6JeSxSBFLWzeLGjFnV/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}