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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e47dd5a6b0723b64e857ae376b953204921109fbc8148da98f48a0b37a16f9f' 
  AND token = 'eo9UpixzOT5L8TcuRE+zpy+rAgJcNMFaDluBMHwnnmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}