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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2493b84ac5dda1542c49e9e1043058c3fe568c0eee542d95b36ea92c2bab6a42' 
  AND token = 'FXBl0CJnXfr9pZG+2vvzJ28Jwl+81lbaUbvbULQsEDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}