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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00d5ba19c06f4879d55f15111a28112635dbf43591606aecb7f7469245333469' 
  AND token = 'CgDB9Vc0OeT4/fgS0O4PDhFLFbbCXqFavywEl0gFSyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}