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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac949ac4b10660ce2ee7f24d1b8254495cfbdbd9c98b647ed375ab15ddfe285' 
  AND token = 'a11fQj8IvIVnDUDnoBIe2lLRXolO7N4r3/gQZm7hYOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}