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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404a10727f9cc1d43f412759a0a29a0dc85e692293b63f6b53aa3990ebd00a26' 
  AND token = 'N0Yj1L1+VkVkEzE1+PjRu8oey7cKVnYAJypdAHBZ4og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}