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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a545888865fa6d46ce82678a8f13166233f3025b3a6d63b262a09bbcfc1a1555' 
  AND token = 'lVzakDmA2mWNHq/2ehPBnBS0TRam/sCZJNbR8XkHL54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}